Does tranexamic acid reduce blood loss and blood transfusion requirement in knee arthroplasty?
O. Şahap Atik
Department of Orthopaedics and Traumatology, Medical Faculty of Gazi University, Ankara, Turkey
Keywords: Blood l oss; b lood t ransfusion; k nee a rthroplasty; tranexamic acid.
Strong evidences which indicate that tranexamic acid reduces blood loss and blood transfusion requirement in patients who are scheduled for total knee arthroplasty are available. However, dose and method of administration, safety and side effects are still controversial issues. The effect of tranexamic acid on thromboembolic events and mortality is still unknown.